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Keeping in moderation
( Boston , MA ) Despite 20 years of reassuring research, many people still avoid caffeinated coffee because they worry about its health effects. However, current research reveals that in moderation—a few cups a day—coffee is a safe beverage that may even offer some health benefits. The September issue of Harvard Women's Health Watch weighs the pros and cons of this popular beverage and eases the concerns of moderate coffee drinkers.
The latest research has not only confirmed that moderate coffee consumption doesn't cause harm, it's also uncovered possible benefits. Studies show that the risk for type 2 diabetes is lower among regular coffee drinkers than among those who don't drink it. Also, coffee may reduce the risk of developing gallstones, discourage the development of colon cancer, improve cognitive function, reduce the risk of liver damage in people at high risk for liver disease, and reduce the risk of Parkinson's disease. Coffee has also been shown to improve endurance performance in long-duration physical activities.
For those who drink coffee to stay alert, new research suggests that you'll stay more alert, particularly if you are fighting sleep deprivation, if you spread your coffee consumption over the course of the day. For instance, if you usually drink 16 ounces in the morning, try consuming a 2-3 ounce serving every hour or so. Again, moderation is the key.
However, as the September issue notes, coffee is not completely innocent. Caffeine, coffee's main ingredient is a mild addictive stimulant. And coffee does have modest cardiovascular effects such as increased heart rate, increased blood pressure, and occasional irregular heartbeat that should be considered. Studies have been largely inconclusive regarding coffee and its effect on women's health issues such as breast health, cancer, and osteoporosis. But, the negative effects of coffee tend to emerge in excessive drinking so it is best to avoid heavy consumption.

Benefits:
- Helps prevent gallstones and symptomatic gallbladder disease in men.
- Contains caffeine-related compounds (theophylline) that can alleviate the symptoms of asthma in some cases.
- Can increase alertness and prolong waking hours.
- May improve short-term recall.
- Promotes the effectiveness of certain pain killers. For this reason some aspirin producers also include a small dose of caffeine in the pill
- May reduce the risk of cirrhosis of the liver among heavy drinkers and prevent colon and bladder cancers. The risk of getting Hepatocellular carcinoma a variety of liver cancer can also be reduced.
- May postpone muscle fatigue and thus enhance athletic performance and endurance.
- May protect against free radical damage to tissues – one study found that coffee has more antioxidant activity than red wine, green or black tea, or orange juice.
- Coffee intake may reduce one's risk of diabetes mellitus type 2 by up to half. While this was originally noticed in patients who consumed high amounts (7 cups a day), the relationship was later shown to be linear (Salazar-Martinez 2004).
- coffee reduces the incidence of heart disease, though this may be simply because it rids the blood of excess fat or because of its stimulant effect is unknown.
At the annual meeting of the American Chemical Society chemist Joe Vinson presented his analysis showing that for Americans, who as a whole do not consume large quantities of fresh fruits and vegetables, coffee represents by far the largest source of valuable antioxidants in the diet.
Coffee contains the anticancer compound methylpyridinium. This compound is not present in significant amounts in other food materials. Methylpyridinium is not present in raw coffee beans but is formed during the roasting process from trigonellin, which is common in raw coffee beans. It is present in both caffeinated and decaffeinated coffee, and even in instant coffee.
Coffee is also a powerful stimulant for peristalsis and is sometimes considered to prevent constipation, it is also a diuretic. However, coffee can also cause loose bowel movements.
Many people drink coffee for its ability to increase short term recall and increase IQ. It also changes the metabolism of a person so that their body burns a higher proportion of lipids to carbohydrates, which can help athletes avoid muscle fatigue.
Some of these health effects are realized by as little as 4 cups a day (24 U.S. fl oz, 700 mL), but others occur at 5 or more cups a day (32 U.S. fl oz or 0.95 L or more).
Some controversy over these effects exists, since by its nature coffee consumption is associated with other behavioral variables. Therefore it has been variously suggested that the cognitive effects of caffeine are limited to those who have not developed a tolerance, or to those who have developed a tolerance and are caffeine-deprived.
Risks:
- Increases blood pressure among people with high blood pressure
- Causes insomnia, anxiety, and irritability.
- May worsen symptoms of PMS in some women.
- Can reduce fertility in women trying to conceive.
- Can cause heartburn and indigestion.
- May increase the risk of osteoporosis in postmenopausal women.
- May increase blood levels of homocysteine and the associated risk of cardiovascular disease.
We should also note that some health authorities remain concerned about the potential effects of coffee drinking on heart disease, fibrocystic breast disease, stomach ulcers, and pancreatic and colorectal cancer, although for the most part recent studies seem to be exonerating coffee on these issues.
You'll probably notice that some people's risks are another's benefits, and that timing can be important – coffee's stimulation is generally more welcome in the morning than late at night. So drink accordingly. Also, keep in mind that, like virtually any herb or other substance you might consume, dosage is also important. Few people will be especially bothered by one or two cups of coffee, but adverse effects are much more likely for those gulping down eight to ten cups per day.
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